Phenylmagnesium chloride

Phenylmagnesium chloride

CAS No.: 100-59-4

Molecular Formula: C6H5ClMg

Molecular Weight: 136.86

Basic Information

Appearance: Light brown to brown liquid

Density: 0.98g/ml (20°C)

Boiling Point: 66°C (refers to the solvent, not the solute)

Flash Point: -17°C

Concentration: 1.0M, 2.0M (tetrahydrofuran solution)

Properties

Reacts violently with water: Extremely sensitive to air and moisture, will react violently with water and release flammable benzene.

Flammable: In humid air, due to the intense exothermic reaction, flammable benzene will be released.

Stability: Should be handled and stored under the protection of anhydrous and oxygen-free inert gases such as nitrogen or argon. Avoid contact with oxidizers, acids, alcohols, etc. at room temperature.

Applications

1. General Grignard reagent: Used as a phenylating reagent for the synthesis of various organic compounds such as alcohols, ketones and carboxylic acids.

2. Pharmaceutical synthesis: Used to synthesize pharmaceutical molecules such as (-)-phenylserine and stephacidin B.

3. Cross-coupling reactions: Participate in a variety of cross-coupling reactions to construct complex molecules.

Packaging/Storage

1. 500ml glass bottles; 200L iron drums and steel cylinders.

2. During use, this product should be isolated from air and moisture to the greatest extent, and it is best to use it up once opened. If color difference or micro-precipitation is found in this product, it will not affect the product performance.

3. Store at room temperature.