Isobutylmagnesium bromide

Isobutylmagnesium bromide

CAS No.: 926-62-5

Molecular Formula: C4H9BrMg

Molecular Weight: 161.32

Basic Information

Appearance: Gray to taupe liquid

Density: 0.941g/ml (25°C)

Boiling Point: 66°C, 80°C (referring to the solvent, not the solute)

Flash Point: -34°C

Concentration: 1.0M, 2.0M (solutions in tetrahydrofuran, 2-methyltetrahydrofuran)

Properties

Reacts violently with water: Extremely sensitive to air and moisture, will react violently with water and release flammable isobutane gas.

Flammable: Its solution is a flammable liquid. In humid air, violent exothermic reaction will occur, releasing flammable isobutane gas.

Stability: It should be operated and stored under the protection of anhydrous and oxygen-free inert gases (such as nitrogen or argon). Avoid contact with oxidants, acids, alcohols, etc. at room temperature.

Applications

1. Pharmaceutical industry: Can be used to synthesize pyrrolidine influenza neuraminidase inhibitors.

2. General Grignard reagent: As an alkylating reagent, it is used to synthesize various organic compounds such as alcohols, ethers and ketones, generating isobutylated products.

Packaging/Storage

1. 500ml glass bottles; 200L iron drums and steel cylinders.

2. During use, this product should be isolated from air and moisture as much as possible, and it is best to use it once immediately after opening. If color difference or micro-precipitation is found in the product, it will not affect the performance of the product.

3. Store at room temperature.