Lithium Diisopropylamide

Lithium Diisopropylamide

CAS No.: 111-54-0

Molecular Formula: [(CH3)2CH]2NLi

Molecular Weight: 107.12

Basic Information

Appearance: Slightly yellow transparent liquid

Density: 0.864g/ml (25°C)

Boiling Point: 66°C (refers to the solvent, not the solute)

Flash Point: -26°C

Concentration: 1.5M, 2.0M (mixed solution of n-heptane, tetrahydrofuran and ethylbenzene)

Properties

Reacts violently with water and air: It reacts instantly with water, releasing flammable gases. Meanwhile, it is extremely sensitive to air.

Flammable: In humid air, due to the intense exothermic reaction, flammable gases are released, and it is extremely prone to catch fire and explode when exposed to open flames, high heat or oxidants.

Stability: It needs to be stored and used at low temperatures.

Applications

1. Regioselective enolization of carbonyl compounds.

2. Preparation of silyl enol ethers and enol ethers.

3. α-alkylation and condensation of esters.

4. Abstraction of other acidic hydrogens.

5. Elimination reactions.

Packaging/Storage

1. 500ml glass bottles; 30L steel cylinders; 300/500L storage tanks.

2. During use, this product should be isolated from air and moisture to the greatest extent, sealed and stored in a dry environment below -5°C, and used under the protection of nitrogen or argon.

3. Avoid high temperature and impact, do not touch open flames, and do not allow contact with air and water. Store at low temperatures.