Tiamulin Fumarate

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Industry Category:	Chemicals/Pesticides/Insecticides
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CAS NO:	55297-96-6
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Description

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TIAMUCIN^® 80

COMPOSITION

TIAMUCIN^® 80 (tiamulin 80%) is a feed premix containing 800 g of Tiamulin Hydrogen Fumarate per kg.

SPECIFICATION

Items Technical Specifications	Specifications
Appearance	white to light yellow granules
pH	From 3.1 to 4.1
Loss on drying	Not more than 3.5%
Assay	95.0%-105.0% of labeled content
Particle size	NLT 80% products in 30-80 mesh

INDICATION

Tiamulin is a semi-synthetic derivative of Pleuromutilin. It is highly active against gram-positive organisms, mycoplasmas and serpulina (Treponema) hyodysenteriae.

Tiamulin is used for prevention and control of mycoplasmal diseases such as enzootic pneumonia and chronic respiratory disease in pigs and poultry; swine dysentery, porcine colonic spirochaetosis and porcine proliferative enteropathy.

DOSAGE

Animal	Disease	Tiamulin (ppm)	Tiamucin^®80 (g/t)	Administration (Day)	Withdraw period (Day)
Swine	Treatment of pneumonia	100-200	125-250	7-10	7
	Prevention of pneumonia	30-50	37.5-62.5	Consecutive use in the period of risk	2
	Treatment of swine dysentery	100-200	125-250	7-10	7
	Prevention of swine dysentery	30-50	37.5-62.5	Consecutive use in the period of risk	2
	Growth promoter	10	12.5	Consecutive use	0
Chicken	Treatment of CRD	200	250	3-5 consecutive days	3
	Prevention and control of CRD in broilers	30	37.5	Consecutive use in the period of risk
	Prevention and control of CRD in breeders and layers and improvement in egg production	50	62.5	One week per month throughout the laying period
	As an aid in the control of CRD in breeders and layers and improvement in egg production and feed conversion efficiency	20	25	Consecutive use throughout the laying period

Premix for Animal Use

CAS NO:55297-96-6

EC NO:259-581-6

Molecular Formula:C₃₂H₅₁NO₈S

Molecular Weight:609.8142

Synonyms:;Tiamuline Hydrogen Fumarate;((2-(DIETHYLAMINO)ETHYL)THIO)ACETIC ACID 8-ESTER WITH (3AS,4R,5S,6S,8R,9R,9AR,10R)-OCTAHYDRO-5,8-DIHYDROXY-4,6,9,10-TETRAMETHYL-6-VINYL-3A,9-PROPANO-3AH-CYCLOPENTACYCLOOCTEN-1(4H)-ONE FUMARATE;DENAGARD;,10-tetramethyl-1-oxo-3-alpha,9-propano-3-alpha-h-cyclopentacycloocten-8-yles;14-deoxy-14-((2-diethylaminoethyl)-mercaptoacetoxy)-mutilinhydrogenfumarate;14-desossi-14-((2-dietilaminoetil)mercapto-acetossi)mutilinidrogenofumarato;81723hfu;dynamutilin;sandoz81723hfu;Tiamulin Fumarate;(4R,5S,6S,8R,9aS,10R)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate (2E)-but-2-enedioate (salt);(3aS,4R,5S,6S,8R,9R,9aR)-6-ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propanocyclopenta[8]annulen-8-yl {[2-(diethylamino)ethyl]sulfanyl}acetate (2E)-but-2-enedioate (salt);

Molecular Structure: