Linaclotide can bind to the guanylate cyclase C-type receptor (GC-C) in the intestinal tract after being taken orally into the human body to increase the intracellular and extracellular cyclic guanylic acid (cGMP) concentration and stimulate the secretion of intestinal juice , To accelerate the migration of the gastrointestinal tract, thereby increasing the frequency of bowel movements. Due to its unique mechanism of action, it is promising to become a therapeutic drug that can not only treat constipation, but also treat abdominal distension, abdominal pain and other clinical symptoms.

CAS NO:551-11-1

EC NO:

Molecular Formula:C₂₀H₃₄O₅

Molecular Weight:354.481

Synonyms:;prostaglandin F2-alpha;Prostaglandin F2A;9,11,15-trihydroxyprosta-5,13-dien-1-oicacid;amoglandin;cyclosin;dinolytic;enzaprost;enzaprostf;glandin;9,11,15-trihydroxyprosta-5,13-dien-1-oic acid;(9alpha,11alpha,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid;

Molecular Structure: