English name: PROTHIOCONAZOLE

Chemical name: 2 - [2 - (1-chlorocyclopropyl) - 3 - (2-chlorophenyl) - 2-hydroxypropyl] - 1H-1,2,4-triazol-3-thione

Other name: Proline

Molecular formula: C₁₄H₁₅Cl₂N₃OS

Molecular weight: 344.26

Physical and chemical properties:

Prothiazole is a triazole fungicide. The pure product is white or light beige powder crystal; Melting point: 139.1~144.5 ℃; Boiling point: (487 ± 50) ℃ (calculated value); Vapor pressure: ＜ 4 × 10-4 mPa（20℃）； Partition coefficient: n-octanol/water LogPow=4.05 (20 ℃, without buffer)

Toxicity:

Acute oral LD50>5000 mg/kg, acute dermal LD50>2000 mg/kg, and acute inhalation LC50>2000 mg/cm3 of albendazole technical drug in rats; The rabbit skin is not irritant, and the rabbit eyes are slightly to moderately irritant; The skin allergy (sensitization) test of guinea pigs showed no sensitization; The maximum non effective dose of the 90 day subchronic feeding toxicity test of the original drug in rats was 280 mg/kg feed; Four mutagenic tests: Ames test, micronucleus test of mouse bone marrow cells, chromosome aberration test of human peripheral blood lymphocytes and gene mutation test of mammalian cells in vitro were negative, and no mutagenic effect was found. Prothiazole technical is a low toxic bactericide.

Function characteristics:

Prothiazole is an inhibitor of sterol demethylation (ergosterol biosynthesis); Prothiazole is mainly used to control many diseases of cereal crops, such as wheat, barley, rape, peanut, rice and beans. It has good control effect on almost all wheat diseases, such as wheat and barley scab, powdery mildew, sheath blight, fusarium wilt, leaf spot, rust, sclerotinia, net spot, and moire. It can also control soil borne diseases of Youlai and peanut, such as sclerotinia, and major leaf diseases, such as gray mold, black spot, brown spot, black shank, sclerotinia and rust. Inhalable bactericide with protective, therapeutic and eradication activities, and long duration.

Dosage form:

Common preparation: 250g/l emulsifiable concentrates; 30% dispersible oil suspension agent. Prothiotebuconazole 40% suspension agent