Basic Information 
Chinese Name: Diethyl malonate, ethyl carotate, ethyl malonate, diethyl carotate
English Name: diethyl malonate
CAS Number: 105-53-3;145601-68-9
EINECS Number: 203-305-9
Molecular Formula: C₇H₁₂O₄
Molecular Weight: 160.17
Physical and Chemical Properties 
Main Components: Content: ≥98%; Acidity (as malonic acid) ≤0.5%.
Chemical Reagent Analytical Grade: Content: ≥99%; Acidity (as malonic acid) ≤0.05%.
Appearance: Colorless liquid with a sweet ether odor.
Melting Point: -50℃
Boiling Point: 199.3℃
Relative Density: 1.0551
Refractive Index: 1.4135
Flash Point: 100℃
Vapor Pressure: 0.344mmHg at 25°C
Solubility: Miscible with alcohols and ethers, soluble in organic solvents such as benzene. Slightly soluble in water. Solubility in water at 20℃ is 2.08g/100ml.
Application Fields 
1. Intermediate in organic synthesis, used in the preparation of 2-amino-4,6-dimethoxypyrimidine. Also used as a plasticizer for nitrocellulose;
2. Widely used in the production of dyes, fragrances, sulfonylurea herbicides, etc. Mainly used to produce ethoxymethylene, alkyl diethyl malonate, and further synthesize pharmaceuticals such as norfloxacin, lomefloxacin, chloroquine, phenylbutazone, etc., as well as synthetic dyes and pigments like benzimidazolone organic pigments;
3. Used as an intermediate in pharmaceuticals such as chloroquine, phenylbutazone, and sulfadoxine;
4. Approved by GB2760-96 as a permitted food flavoring. Mainly used in the formulation of fruit flavors such as pear, apple, grape, cherry, etc.;